Melanie Nicol, PharmD, PhD
Titles
Education
North Carolina Collaborative Clinical Pharmacology NIH Postdoctoral Training Program, UNC-Duke, Chapel Hill, NC
PharmD, Ohio Northern University Raabe College of Pharmacy
PhD, Pharmaceutical Sciences, UNC Eshelman School of Pharmacy, Chapel Hill, NC
Licensures and Certifications
Biography
Expertise
HIV and Opportunistic Infections
HIV/AIDS
Clinical Pharmacology
Women's Health
Drug Metabolism and Transport
Awards & Recognition
Deborah E. Powell Center for Women's Health Research Scholar
Professional Associations
Society of Infectious Disease Pharmacists
American Society of Clinical Pharmacology and Therapeutics
American Association of Pharmaceutical Scientists
American College of Clinical Pharmacy
Research Summary
Our research efforts are focused on identifying factors that influence the efficacy of antivirals (and other anti-infectives) in tissue compartments. We are working to describe the penetration of drugs used to treat HIV and related infections into tissue compartments such as the genitals, brain, and lymph tissue. There is a paucity of data on the factors that modulate drug efficacy in tissue compartments yet drug distribution to these tissues is critically important for HIV prophylaxis, suppression of viral shedding, and eradication of viral reservoirs. Our translational lab uses a variety of research approaches with projects spanning in vitro, ex vivo, and clinical studies. We have active studies in both Minnesota as well as Kampala, Uganda.
Teaching
Teaching Areas
Antivirals; Pharmacotherapy of Infectious Disease
Courses
PHAR 6768: Infectious Disease