Daniel Keyler, PharmD, FAACT

Dr. Keyler's interest in animal venoms intensified during his high school/college academic years when he was mentored by the eminent immunologist and herpetologist, Professor Sherman A. Minton, Jr., MD. He maintained a friendship and professional relationship with Dr. Minton via patient envenomation consultations until his passing in 1999. Dan’s interest continued to expand into the realm of toxicology, and he completed university courses in Environmental Toxicology, Industrial Toxicology, Veterinary Toxicology, Clinical Toxicology, General Toxicology, Advanced Toxicology, and Research Toxicology. Dr. Keyler holds a BS degree from Purdue University in Science, and BS in Pharmacy and Doctor of Pharmacy degrees from the University of Minnesota. Continued involvement with the discipline of toxicology followed as Dan was on the Medical Faculty, Division of Clinical Pharmacology and Toxicology, Department of Medicine, Hennepin County Medical Center (1985-2011). He concurrently served as Co-Director of Toxicology Research with the Minneapolis Medical Research Foundation , where he developed antibodies and vaccines as immunotherapeutic agents against toxic compounds and toxins.

He served as President of the North American Society of Toxinology 2016-18, is a Fellow of the American Academy of Clinical Toxicology, and Adjunct and Clinical Professor, Department of Experimental & Clinical Pharmacology, University of Minnesota, College of Pharmacy (where he developed the first course in Clinical Toxinology). He also is a Senior Consulting Clinical Toxicologist for SafetyCall International. Dan has consulted clinically on hundreds of snakebite envenoming cases, and has objectively contributed to the fields of toxicology and toxinology, having authored/coauthored over 100 peer-reviewed scientific publications and 40 book chapters involving immunotherapeutics (antibody and vaccine development), immunotoxicology, toxicology, animal toxins, and venomous snakebite. He has been a coauthor and editor for three books; the 1st edition, Venomous Bites from Non-Venomous Snakes: A Critical Analysis of Risk Management of Colubrid Snake Bites (2011); Venomous Snakebite in the Western United States (2005), and the 2nd edition, Venomous Bites from Non-Venomous Snakes (2023). He served as Chair of the Envenomation Section with the American Academy of Clinical Toxicology 2002-07 and is a member of the Medical Advisory Committee for the Online Antivenom Index.

Dr. Keyler is a reviewer for multiple medical and scientific journals, envenomation consultant to multiple zoos, and a member of the International Society on Toxinology, American Academy of Clinical Toxicology, North American Society of Toxinology, and Society for the Study of Amphibians and Reptiles. Dr. Keyler has had a lifelong interest in Timber Rattlesnakes (Crotalus horridus) and has had multiple research grants to study this species in the Upper Mississippi River Valley, and he is a founding member of a committee involved in the development of a national Conservation Action Plan regarding C. horridus and has ongoing interest in the biology and venom of C. horridus. Dr. Keyler continues field work with venomous species and collaborates with antivenom development in temperate and tropical geographic regions of the world.

Immunotoxicology, toxinology, and venomous snakes and clinical management of venomous snakebite.

• Fellow, American Academy of Clinical Toxicology, 2011
• Samuel W. Melendy Lecturer, 2010, College of Pharmacy, University of Minnesota
• Research Fellow Award, American Academy of Clinical Toxicology, 1985

• American Academy of Clinical Toxicology
• International Society on Toxinology
• North American Society of Toxinology

30+ years developing antibodies and vaccines against drugs (as antidote for drug overdose), toxicants (polychlorinated biphenyls), drugs of addiction (nicotine and opiates), and snake antivenoms.

Clinical Toxicology

Developed the first course in Clinical Toxinology with the College of Pharmacy.

Clinical Interests

Clinical treatment of patients envenomated by snakes, spiders, scorpions, jellyfish, and multiple venomous creatures

Clinical Experience Statement

Over 40 yrs experience in treating envenomations from multiple venomous species with the use of immunotherapeutic agents.