Dr. Philip S. Portoghese is an internationally known chemist and researcher. Perhaps most well known for designing several opioid ligands including β-funaltrexamine, naltrindole, norbinaltorphimine, and naltriben, he pioneered the use of bivalent ligands to target opioid receptor complexes called heteromers. In his honor, the Philip S. Portoghese Distinguished Lecture in Medicinal Chemistry has been established to recognize scientists who have made outstanding contributions to medicinal chemistry.
2024 Portoghese Lecture
Portoghese Lectures by Year
2015 - 2019
Fall 2019
Dr. Maria-Laura Bolognesi
University of Bologna
"Principles, Implementation, and Application of Multitarget Drug Discovery in Alzheimer’s Disease"
Fall 2018
Dr. P. Jeffrey Conn
Vanderbilt University
"Allosteric Modulators of GPCRs as a Novel Approach for Treatment of Schizophrenias"
Spring 2018
Dr. Richard A. Glennon
Virginia Commonwealth University
"Drug Discrimination: A Behavioral Technique to Investigate Centrally-acting Agents"
2016
Dr. Lawrence Marnett
Vanderbilt University
"Allosteric Inhibition of Cyclooxygenases and the Mechanism of Action of NSAIDS"
2015
Dr. Bryan Roth
University of North Carolina - Chapel Hill
"Genome wide approaches to GPCR chemical biology"
2020 - 2024
2022
Dr. Andreas Plückthun
University of Zurich
"Therapeutic Proteins: From engineering to in situ delivery"